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Bone loss in the elderly

J A Kanis1, S Adami

  • 1Department of Human Metabolism and Clinical Biochemistry, University of Sheffield Medical School, UK.

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
|January 1, 1994
PubMed
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Bone loss continues throughout life, even accelerating after age 70. This finding supports the value of assessing fracture risk and treating bone metabolism in all age groups, including the elderly.

Area of Science:

  • Gerontology
  • Bone Metabolism
  • Osteoporosis Research

Background:

  • Cross-sectional studies suggest reduced bone loss in the elderly.
  • This has led to the belief that bone mass measurements and bone-active drugs are less effective in older adults.
  • This paper challenges these assumptions.

Purpose of the Study:

  • To review and critique the assumptions underlying the belief that bone loss and its treatment are less relevant in the elderly.
  • To present evidence that bone loss continues throughout life.

Main Methods:

  • Review of existing literature and cross-sectional studies.
  • Examination of direct and biochemical indices of bone turnover in the elderly.
  • Analysis of assumptions regarding age-related bone loss.

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Main Results:

  • Evidence suggests bone loss continues throughout life.
  • Bone loss may accelerate in individuals over 70 years of age.
  • Assumptions about decreased bone loss in the elderly are often flawed.

Conclusions:

  • Bone loss is a continuous process across all adult age groups.
  • Bone mass measurements and interventions targeting bone metabolism are valuable for assessing and managing fracture risk in the elderly.
  • Continued research and clinical attention to bone health in older populations are warranted.