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Protein kinase C inhibitors; structure-activity relationships in K252c-related compounds
1Université Blaise Pascal, Laboratoire de Chimie Organique Biologique, URA 485, Aubière, France.
Bioorganic & Medicinal Chemistry
|September 1, 1993
Abstract:
K252c-related compounds were synthesized with different framework flexibilities and different functions (imide, amide and amide-alcohol) on the non-indolic heterocycle. The inhibitory activities towards protein kinase C and protein kinase A are compared.