[A case-control study on risk factors in etiology of Parkinson's disease]

Risk factors of Parkinson's disease (PD) were studied by the case-control method (1:1) in 90 cases. It was suggested that the high positive rate (34.4%) in PD family history was related to "genetic susceptibility". There was history of head injury, rheumatic fever, seizure, taking anti-psychosis drug or contact with toxins, but any one factor could not completely explain the etiology of PD. We believe that coordinating effects of both susceptibility in genetics and environmental toxins may explain the mechanism of PD.