[Cytomegalovirus infection in pregnant women and perinatal infants]

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Updated: Oct 13, 2026

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
05:53

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates

Published on: July 6, 2013

R M Yang1, C Y Gu, T X Li

  • 1Yanan Hospital, Kuming.

Zhonghua Fu Chan Ke Za Zhi
|March 1, 1994
PubMed

Perinatal cytomegalovirus (CMV) infection was studied, using method of CMV-IgM ELISA, in 256 pregnant women at different periods and in the cord blood of 84 babies born by CMV positive mothers. Results showed that in 42 cases at early and midtrimester pregnancy, 17 were CMV-IgM positive with an infection rate of 40.48%. Among the 214 women at late pregnancy, 84 were positive (39.25%). There was a higher prevalence of perinatal morbidity, neonatal asphyxia, malformation, intrauterine death, and poor obstetrical outcome in the CMV positive mothers as compared with the CMV negative group (P < 0.01). This study showed that the presence of CMV-IgM indicated a recent or recurrent CMV infection during pregnancy and the babies should be carefully monitored.

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