Formation and lateralization of internal representations underlying motor commands during precision grip
Related Experiment Video
Updated: Nov 10, 2026

Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury
Published on: March 21, 2025
A M Gordon1, H Forssberg, N Iwasaki
1Nobel Institute for Neurophysiology, Karolinska Institute, Stockholm, Sweden.
Abstract:
The capability to store and retrieve weight-related information from a lift to scale the force output during a subsequent lift was examined in 10 healthy adults and 50 children (age 2-10 years), as well as a 22-year-old patient with corpus callosum agenesis. Subjects lifted a test object between the thumb and index finger while the isometric fingertip forces were measured. The results suggest that both healthy children and adults can transfer weight-related information between the right and left hand, although a lateralization was found. Also, the storage and retrieval of weight-related information appears to be a dynamic process dependent on both previous sensory information and knowledge of future movements. Late maturation of interhemispheric connections and asymmetric loss of some information during the transfer between hemispheres suggest a lateralization of the internal representation. The patient with a corpus callosum agenesis supported this hypothesis.
Related Concept Videos
Hand Control During Infancy and Toddlerhood
Principles of Development
Hierarchy of Motor Control
Motor and Sensory Areas of the Cortex
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Somatosensation
Motor Skills Development During Early Childhood

