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Hostile personality and risks of peripheral arterial disease in the general population

I J Deary1, F G Fowkes, P T Donnan

  • 1Department of Psychology, University of Edinburgh, UK.

Insights

Hostile personality traits are linked to increased risk of peripheral arterial disease, especially in men. This study found a connection between hostile acts and claudication, independent of other risk factors.

Area of Science:

  • Cardiovascular Epidemiology
  • Behavioral Medicine
  • Psychosomatic Medicine

Background:

  • Established links between personality and coronary heart disease risk.
  • Limited research on personality and other atherosclerotic diseases, such as peripheral arterial disease.

Purpose of the Study:

  • To investigate the association between hostile personality and Type A behavior pattern with asymptomatic and symptomatic chronic peripheral arterial disease in the general population.

Main Methods:

  • Cross-sectional study of 1592 individuals aged 55-74 years (Edinburgh Artery Study).
  • Assessed peripheral arterial disease via intermittent claudication questionnaire, ankle brachial pressure index, and reactive hyperemia test.
  • Measured personality using the Bedford Foulds personality deviance questionnaire and Bortner self-administered questionnaire for Type A/B behavior.

Main Results:

  • Hostile acts scores increased with peripheral arterial disease severity (p < .05).
  • Increased risk of claudication associated with hostile acts was significant in males (OR, 1.41; p < .05), independent of smoking, alcohol, obesity, and diabetes.
  • Dominance personality traits were linked to asymptomatic peripheral arterial disease.
  • Type A personality scores unexpectedly decreased with peripheral arterial disease severity.

Conclusions:

  • Hostile personality may be an independent risk factor for chronic peripheral arterial disease, particularly in men.
  • Further research is warranted to explore the mechanisms linking personality to atherosclerotic disease development.

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