[Use of 3rd generation cephalosporins in antimicrobial prophylaxis in surgery]

In a general and special review the authors discuss contemporary possibilities of antimicrobial prophylaxis in surgery focused on cephalosporins of the third generation. According to available data on the incidence of resistance, pharmacokinetics and others the most suitable preparations seem to be cefotaxime and ceftriaxone. They are used in particular in thoracic surgery, hepatobiliary surgery, colorectal surgery and urology.