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Antimicrobial susceptibility of Pasteurella haemolytica and Pasteurella multocida isolated from pneumonic ovine lungs
K S Diker1, M Akan, R Haziroglu
1Department of Microbiology, Faculty of Veterinary Medicine, Ankara University, Turkey.
Abstract:
The in vitro susceptibilities of Pasteurella haemolytica biotypes A and T and P multocida from pneumonic ovine lungs to penicillin, ampicillin, oxytetracycline, chloramphenicol, erythromycin, kanamycin, neomycin, gentamicin, streptomycin and lincomycin were determined by the disk diffusion method. All the isolates were sensitive to chloramphenicol and resistant to lincomycin. The isolates of P haemolytica biotype A were consistently more sensitive to penicillin, ampicillin, oxytetracycline, erythromycin and streptomycin than those of biotype T.
Insights
This study evaluated antibiotic susceptibility in ovine pneumonia pathogens. Pasteurella haemolytica biotype A showed greater sensitivity to several antibiotics compared to biotype T.
Area of Science:
- Veterinary Microbiology
- Animal Health
- Antimicrobial Resistance
Background:
- Ovine pneumonia is a significant concern in sheep farming.
- Pasteurella species are key bacterial pathogens associated with ovine pneumonia.
- Understanding antibiotic susceptibility is crucial for effective treatment strategies.
Purpose of the Study:
- To determine the in vitro antibiotic susceptibility profiles of Pasteurella haemolytica biotypes A and T, and Pasteurella multocida isolated from ovine lungs.
- To compare the susceptibility patterns between different Pasteurella haemolytica biotypes.
Main Methods:
- Disk diffusion method was employed to test the susceptibility of bacterial isolates.
- A panel of ten antibiotics was evaluated against the ovine isolates.
Main Results:
- All tested isolates demonstrated sensitivity to chloramphenicol.
- All isolates exhibited resistance to lincomycin.
- Pasteurella haemolytica biotype A isolates were consistently more susceptible to penicillin, ampicillin, oxytetracycline, erythromycin, and streptomycin than biotype T isolates.
Conclusions:
- Chloramphenicol is effective against these ovine Pasteurella isolates, while lincomycin is not.
- Distinct antibiotic susceptibility differences exist between Pasteurella haemolytica biotypes A and T, informing targeted therapeutic choices.