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Preparation and characterization of monoclonal antibodies against equine chondrocytes, osteoblasts and osteocytes
Y Katayama1, M Oikawa, M Kaneko
1Pathology Division, Equine Research Institute, Japan Racing Association, Tokyo.
Zentralblatt Fur Veterinarmedizin. Reihe A
|February 1, 1994
Abstract:
Three monoclonal antibodies capable of individually recognizing chondrocytes, osteoblasts and osteocytes were prepared. EB-1 reacted with a 55-kDa antigen on the chondrocyte membrane, EB-2 with a 110-kDa antigen on the membrane of osteoblasts and/or partial osteocytes, and EB-3 with a 130-kDa antigen on the membrane of osteocytes. These monoclonal antibodies may be useful probes for studying the differentiation and maturation of osteogenic cells.