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Nucleolar size and mitotic index in basal cell carcinomas (BCC) and squamous cell carcinomas (SCC) of canine skin
G De Vico1, U Agrimi, P Maiolino
1Department of Veterinary Pathology, Faculty of Veterinary Medicine, Federico II University, Naples, Italy.
Abstract:
Nine squamous cell carcinomas (SCC) and ten basal cell carcinomas (BCC) of the dog's skin were retrospectively evaluated from the point of view of both their nucleolar size and their mitotic index. With the exception of one, all SCC samples under investigation were non-metastasizing. Mean nucleolar area/cell ranged from 4.36 to 9.87 microns 2 in SCC, and from 1.06 to 2.59 microns 2 in BCC samples. A significant statistical correlation could be demonstrated between cell nucleolar area and mitotic index in SCC samples.