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[Analysis of renal water excretion in full-term newborn infants]
1Department of Pediatrics, Tri-Service General Hospital, Taipei, Taiwan, R.O.C.
Insights
Newborn infants can efficiently excrete large volumes of dilute urine after increased milk intake. This study shows renal water excretion adapts to fluid intake in healthy newborns.
Area of Science:
- Neonatal physiology
- Renal function
- Pediatric nephrology
Abstract:
The response of renal water excretion was studied in 33 healthy 1-2 day-old and 6-7 day-old full-term newborn infants. With increasing milk intake (fluid intake) in 6-7 day-old newborn infants, there was not only a significant increase of urine flow, urinary sodium excretion was also significantly increased with urine amount (p < 0.01). There was no significant differences of serum osmolality and serum sodium between 1-2 day-old and 6-7 day-old newborn infants, but there was a significant decrease of urine osmolality (p < 0.01) in 6-7 day-old infants. It is suggested that following high fluid (milk) intake full-term infants are capable of adaptively excreting large urine volume and more dilute urine.