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Reflex sympathetic dystrophy involving three limbs: a case study

R W Teasell1, P Potter, D Moulin

  • 1Department of Physical Medicine and Rehabilitation, University Hospital, London, Ontario, Canada.

Archives of Physical Medicine and Rehabilitation
|September 1, 1994
PubMed
Summary
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Reflex sympathetic dystrophy (RSD) can affect multiple limbs, challenging the traditional view of sympathetic nervous system dysfunction. This case suggests a significant central nervous system role in the complex pathophysiology of RSD.

Area of Science:

  • Neurology
  • Pain Medicine

Background:

  • Reflex sympathetic dystrophy (RSD) is typically characterized by unilateral limb pain, hyperesthesia, and vasomotor instability.
  • It has been historically attributed to sympathetic nervous system dysfunction, often improving with sympathetic blockade.

Observation:

  • An atypical case of three-limb RSD is presented, involving the right lower extremity, left upper extremity, and left lower extremity.
  • Each affected limb progressed to develop dystrophic changes.

Findings:

  • The development of RSD in multiple, non-contiguous limbs suggests a pathophysiology beyond localized sympathetic dysfunction.
  • This case highlights the potential involvement of the central nervous system in the progression of RSD.

Implications:

Related Experiment Videos

  • The findings suggest that central nervous system mechanisms play a crucial role in the development and spread of RSD.
  • Further research into central nervous system pathways is warranted to understand and treat complex RSD cases.