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Updated: Oct 2, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
[Acute pancreatitis--are there diagnostically and prognostically relevant chemical laboratory parameters?]
C Dressler1, K P Franke, M Herzig
1Krankenhausbetrieb von Berlin Friedrichshain.
Abstract:
The diagnosis "acute pancreatitis" is a tentative clinical diagnosis. Pathognomonic and specific laboratory findings are missing. According to the relevant literature, the diagnostically and prognostically relevant laboratory values include methaemoglobin, magnesium and calcium blood levels and amylase in serum and in urine. We investigated nine cases of acute haemorrhagic necrotising pancreatitis. The diagnosis was verified operatively and with the help of computer tomography. Only the calcium blood level has prognostic value. A calcium level below 2.2 mmol/l is an important symptom for prognosis and outcome.
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Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
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Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
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Assessment:
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