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[Acute oral acetic acid poisoning--case report]
1Klinik für Anästhesiologie und Intensivmedizin, Klinikums Frankfurt/Oder.
Summary
A patient survived a lethal dose of acetic acid via prompt medical intervention. Key treatments included plasma separation for detoxification and managing haemolysis and renal failure, leading to recovery.
Area of Science:
- Toxicology
- Internal Medicine
- Emergency Medicine
Background:
- Acetic acid ingestion, especially in large quantities (400 ml of 25% solution), presents a critical medical emergency.
- Severe corrosive injuries necessitate immediate airway management, including intubation and ventilation.
Observation:
- The patient presented with pain, shock, haemolysis, and renal failure 2 hours post-ingestion.
- Symptoms indicated severe systemic toxicity following the ingestion of a potentially lethal dose of acetic acid.
Findings:
- Plasma separation proved effective for rapid detoxification and removal of haemolysis products.
- Management involved addressing haemolysis, renal failure, acid-base balance, and potential disseminated intravascular coagulation.
- Treatment included erythrocyte transfusion, AT III substitution, and haemodialysis for secondary renal failure.
Implications:
- This case highlights the critical importance of immediate haemolysis treatment and detoxification via plasma separation.
- Prompt and comprehensive management, including supportive care and interventions like plasma separation and transfusions, can lead to favorable outcomes even in severe acetic acid poisoning.