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Diabetic ketoacidosis associated with pulmonary coccidioidomycosis
1Department of Medicine, Maricopa Medical Center, Phoenix, Arizona 85008.
Abstract:
We describe three patients who developed diabetic ketoacidosis in association with pulmonary coccidioidomycosis and review the literature concerning the influence of diabetes on coccidioidomycosis. Our cases demonstrate that coccidioidomycosis is an infection that can be associated with diabetic ketoacidosis and that should be considered in the differential diagnosis of pneumonia in patients who live in a region in which Coccidioides immitis is endemic.
Insights
Diabetic ketoacidosis can occur with pulmonary coccidioidomycosis. This fungal infection should be considered in pneumonia diagnoses for endemic region residents.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Endocrinology
Background:
- Diabetes mellitus is a chronic metabolic disorder.
- Coccidioidomycosis is a fungal infection endemic to specific regions.
- Diabetic ketoacidosis is a serious complication of diabetes.
Observation:
- Three patients presented with diabetic ketoacidosis concurrently with pulmonary coccidioidomycosis.
- A review of existing literature on diabetes and coccidioidomycosis was conducted.
Findings:
- Pulmonary coccidioidomycosis is identified as a potential trigger for diabetic ketoacidosis.
- The study highlights a significant association between these two conditions.
Implications:
- Coccidioidomycosis should be included in the differential diagnosis for pneumonia in endemic areas, especially in diabetic patients.
- Increased awareness can lead to earlier diagnosis and management of coccidioidomycosis in diabetic patients.
- This association underscores the importance of considering co-existing infections in patients with metabolic complications.