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Related Experiment Videos

Antibiotic-associated pseudomembranous enteritis due to Clostridium difficile

B Tsutaoka1, J Hansen, D Johnson

  • 1Pharmacy Service, Veterans Affairs Medical Center, Palo Alto, California 94304.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|June 1, 1994
PubMed
Summary

Pseudomembranous enteritis, a rare condition affecting the small and large intestines, can occur after antibiotic use. This case highlights Clostridium difficile as the likely cause, identified by characteristic lesions and toxin A.

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Microbiology

Background:

  • Pseudomembranous colitis is a known complication of antibiotic therapy.
  • Small intestinal involvement in pseudomembranous disease is infrequently reported.

Observation:

  • A patient developed pseudomembranous enteritis affecting both the small and large intestines.
  • The condition arose subsequent to antibiotic exposure.

Findings:

  • Characteristic pseudomembranous lesions were observed.
  • Enzyme-linked immunosorbent assay (ELISA) for Clostridium difficile toxin A in an ileal tissue specimen was positive.

Implications:

  • This case expands the known spectrum of Clostridium difficile infection.

Related Experiment Videos

  • Highlights the importance of considering small intestinal involvement in antibiotic-associated enteritis.
  • Suggests Clostridium difficile as a potential cause of pseudomembranous enteritis.