Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Long-term oxygen therapy

F Ioli1, A Braghiroli, C F Donner

  • 1Clinica del Lavoro Foundation, IRCCS, Veruno (NO) Italy.

Monaldi Archives for Chest Disease = Archivio Monaldi Per Le Malattie Del Torace
|June 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Study of correlation between forced vital capacity and demand for healthcare services in severe asthmatics.

Multidisciplinary respiratory medicine·2015
Same author

The clinical and integrated management of COPD.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG·2014
Same author

Efficacy and safety of maxillomandibular advancement in treatment of obstructive sleep apnoea syndrome.

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2013
Same author

Sleep disturbances in the critically ill patients: role of delirium and sedative agents.

Minerva anestesiologica·2011
Same author

Candidate genes for COPD in two large data sets.

The European respiratory journal·2010
Same author

Standards of care and clinical predictors in patients hospitalised for a COPD exacerbation--the Italian SOS (Stratification Observational Study).

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2010
Same journal

Preventable yet persistent: silicosis and gaps in public health policy - a narrative review.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

Takotsubo syndrome due to occupational stress in a physician.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

Spirometry after treatment completion for pulmonary tuberculosis - a necessity?

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

Heart failure at the crossroads of climate change and environmental health: emerging risks, mechanistic insights, and future directions.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

Aspiration pneumonia in stroke survivors: prevalence and clinical associations at Bolan Medical Complex.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
Same journal

The silent fractures: unmasking osteoporosis in south Indian chronic obstructive pulmonary disease patients.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace·2026
See all related articles

Long-term oxygen therapy (LTOT) improves survival and reduces pulmonary hypertension in COPD patients. Current guidelines recommend LTOT for specific hypoxemia levels, though indications for other lung diseases require further research.

Area of Science:

  • Pulmonary Medicine
  • Respiratory Physiology

Background:

  • Tissue hypoxia correction via oxygen therapy improves survival and reduces pulmonary hypertension in COPD patients.
  • Long-term oxygen therapy (LTOT) is recommended for COPD patients with PaO2 ≤ 7.3 kPa or specific criteria for chronic hypoxemia.

Purpose of the Study:

  • To review the established indications and emerging questions surrounding Long-term Oxygen Therapy (LTOT) in various respiratory conditions.
  • To highlight the benefits of LTOT in COPD and discuss controversies in its application for other lung diseases.

Main Methods:

  • Review of controlled studies and clinical guidelines on oxygen therapy.
  • Analysis of established and debated indications for LTOT.
  • Discussion of oxygen delivery methods and remaining research questions.

Related Experiment Videos

Main Results:

  • LTOT significantly increases survival and reduces pulmonary hypertension in COPD patients with hypoxia.
  • Specific PaO2 thresholds and associated conditions (hematocrit, pulmonary hypertension) guide LTOT prescription.
  • Indications for LTOT in restrictive lung diseases remain controversial; smoking status can affect prescription.

Conclusions:

  • LTOT is a vital treatment for hypoxic COPD patients, improving survival and cardiorespiratory parameters.
  • Further research is needed to clarify LTOT's role in restrictive lung diseases, sleep/exercise desaturations, and its long-term physiological effects.