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Related Experiment Videos

Detrusor pressure in bladder outlet obstruction

R M Anikwe

    Urology
    |August 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Bladder outlet obstruction in men can be accurately diagnosed by measuring detrusor pressure, not just urinary flow rate. Post-surgery, detrusor pressure normalizes, confirming effective treatment for benign prostatic hypertrophy.

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    Area of Science:

    • Urology
    • Nephrology
    • Andrology

    Background:

    • Benign prostatic hypertrophy (BPH) is a common cause of bladder outlet obstruction (BOO) in aging men.
    • Clinical assessment of BOO can be unreliable for determining obstruction severity.
    • Urodynamic studies are crucial for evaluating lower urinary tract symptoms.

    Purpose of the Study:

    • To evaluate the diagnostic accuracy of detrusor pressure versus urinary flow rate in identifying bladder outlet obstruction.
    • To assess the effectiveness of prostatectomy in normalizing detrusor pressure.
    • To determine the correlation between chronic urinary retention and detrusor muscle contractility.

    Main Methods:

    • Synchronous urodynamic studies, including urinary flow rate and detrusor pressure measurements.

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  • Inclusion of 51 adult males: 12 healthy controls and 39 with varying degrees of BOO due to BPH.
  • Pre- and post-operative pressure assessments after prostatectomy.

    • Main Results:

    • Mean maximum detrusor pressure of 50 mm Hg or higher indicated BOO.
    • Elevated detrusor pressures normalized post-prostatectomy.
    • Clinical findings alone were insufficient for estimating maximum detrusor pressure.
    • Detrusor pressure measurement proved superior to flow rate for diagnosing BOO.

    Conclusions:

    • Detrusor pressure recording is a more reliable urodynamic test for bladder outlet obstruction than urinary flow rate.
    • Urinary flow rate remains a valuable screening tool for assessing bladder outlet drainage.
    • Prostatectomy effectively resolves elevated detrusor pressures associated with BPH.