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Concomitant chemoradiotherapy for non-small cell lung cancer
E E Vokes1, D J Haraf, P C Hoffman
1Department of Medicine, University of Chicago, IL 60637-1470.
Lung Cancer (Amsterdam, Netherlands)
|March 1, 1994
Summary
Concomitant chemoradiotherapy is an experimental treatment for advanced non-small cell lung cancer. This review covers the rationale, experience, and clinical trials of this approach.
Area of Science:
- Oncology
- Medical Research
- Clinical Trials
Background:
- Locoregionally advanced non-small cell lung cancer (NSCLC) requires effective treatment strategies.
- Chemoradiotherapy is an emerging treatment modality for NSCLC.
Purpose of the Study:
- To review the theoretical rationale for concomitant chemoradiotherapy in NSCLC.
- To summarize clinical experience and trials of this treatment approach.
Main Methods:
- Literature review of the theoretical basis for combined therapy.
- Summary of clinical trial data from the University of Chicago.
Main Results:
- The review covers the rationale and existing clinical experience.
- Specific clinical trials conducted at the University of Chicago are detailed.
Conclusions:
- Concomitant chemoradiotherapy is an investigational approach for advanced NSCLC.
- Further research and clinical trials are essential to establish its efficacy.