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Updated: Aug 19, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
Factors confounding evaluation of treatment effect in lung cancer
1Department of Oncology, Rigshospitalet, Copenhagen, Denmark.
Abstract:
Disease extent, performance status (PS), and serum lactate dehydrogenase (LDH) are the most important prognostic factors in both inoperable non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Hyponatremia and serum alkaline phosphatase play an additional role in SCLC. Many different stratification algorithms have been proposed in SCLC but a general consensus cannot be achieved before it is decided whether stage of disease should rank above or be included in an algorithm, along with other prognostic factors.
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