Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Silver nitrate ophthalmic solution and chemical conjunctivities

H Nishida, H M Risemberg

    Pediatrics
    |September 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Group I intron located in PR protein homologue gene in Youngia japonica.

    Bioscience, biotechnology, and biochemistry·2000
    Same author

    Synthesis and diuretic activity of bicyclic fused heterocycles containing oxime-O-sulfonic acid moiety.

    European journal of medicinal chemistry·2000
    Same author

    The epidemiological study on registered cases of sudden infant death syndrome (SIDS) in Tokyo: examination of the effect of autopsy on diagnosis of SIDS and the mortality statistics in Japan.

    Forensic science international·2000
    Same author

    Electrocochleographic study in patients with vestibular schwannomas and U-shaped audiograms.

    Audiology : official organ of the International Society of Audiology·2000
    Same author

    Transcatheter arterial chemoembolization therapy using iodized oil for patients with unresectable hepatocellular carcinoma: evaluation of three kinds of regimens and analysis of prognostic factors.

    Cancer·2000
    Same author

    Effect on the incidence of SIDS due to amendment of the death certificate form in Japan.

    The American journal of forensic medicine and pathology·2000

    Many hospitals avoid silver nitrate for newborn eye infections due to chemical conjunctivitis. However, this irritation is temporary and does not increase infection risk, supporting silver nitrate

    Area of Science:

    • Neonatal care
    • Ophthalmology
    • Infectious disease prevention

    Background:

    • Ophthalmia neonatorum prophylaxis is crucial for preventing neonatal eye infections.
    • Silver nitrate is a common prophylactic agent, but concerns exist regarding chemical conjunctivitis.
    • Current nursery practices vary, with some institutions avoiding silver nitrate due to adverse effects.

    Purpose of the Study:

    • To survey current nursery practices for ophthalmia neonatorum prophylaxis.
    • To evaluate the clinical significance and incidence of chemical conjunctivitis following silver nitrate instillation.
    • To assess the efficacy of silver nitrate against common bacterial pathogens.

    Main Methods:

    • Mail questionnaire survey sent to 100 leading maternity hospitals regarding prophylaxis routines.

    Related Experiment Videos

  • Clinical study involving 1,000 newborns with varied eye handling procedures.
  • In vitro susceptibility testing of silver nitrate against Neisseria gonorrhoeae, Staphylococcus aureus, and Escherichia coli.

    • Main Results:

    • Over 20% of surveyed hospitals do not use silver nitrate, citing chemical conjunctivitis as a primary reason.
    • In 1,000 newborns, 90% experienced conjunctivitis within hours of silver nitrate instillation, but most resolved within 24 hours.
    • Rinsing eyes after silver nitrate instillation did not reduce irritation; chemical conjunctivitis did not increase secondary or mask bacterial infections.
    • Silver nitrate demonstrated in vitro effectiveness against Neisseria gonorrhoeae (0.1%), Staphylococcus aureus (0.1%), and Escherichia coli (0.01%).

    Conclusions:

    • Chemical conjunctivitis from silver nitrate is common but transient and clinically insignificant.
    • The prophylactic benefits of silver nitrate in preventing ophthalmia neonatorum outweigh the risks of temporary chemical irritation.
    • Standardized use of silver nitrate for ophthalmia neonatorum prophylaxis should be maintained.