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Feto-maternal plasma phenylalanine concentration gradient from 19 weeks gestation to term
W E Schoonheyt1, J T Clarke, W B Hanley
1Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
Abstract:
Plasma phenylalanine concentrations in fetal blood, obtained by cordocentesis, were compared with simultaneous peripheral venous plasma phenylalanine levels in mothers. The feto-maternal phenylalanine concentration ratio showed a gradual decrease from 19 weeks of gestation to term with an overall ratio of 1.35 +/- 0.42 (mean +/- S.D., n = 14).