Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mohs micrographic surgery local recurrences

G J Hruza1

  • 1Cutaneous Surgery Center, Washington University School of Medicine, St. Louis, Missouri 63110.

The Journal of Dermatologic Surgery and Oncology
|September 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Varicella-zoster and herpes simplex virus reactivation post-COVID-19 vaccination: a review of 40 cases in an International Dermatology Registry.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021
Same author

Cold and COVID: recurrent pernio during the COVID-19 pandemic.

The British journal of dermatology·2021
Same author

Selective non-ablative wrinkle reduction by laser.

Archives of facial plastic surgery·2001
Same author

Laser treatment of facial vascular lesions.

Facial plastic surgery : FPS·2001
Same author

Dermabrasion.

Facial plastic surgery clinics of North America·2001
Same author

Immediate postoperative laser resurfacing improves second intention healing on the nose: 5-year experience.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2001
Same journal

Malignant fibrous histiocytoma at the site of total knee replacement.

The Journal of dermatologic surgery and oncology·1994
Same journal

Basal cell carcinoma arising in a surgical scar: reconstructive surgical treatment.

The Journal of dermatologic surgery and oncology·1994
Same journal

The use of hyaluronidase as an adjunct to surgical procedures.

The Journal of dermatologic surgery and oncology·1994
Same journal

Repair of the soft triangle of the nose.

The Journal of dermatologic surgery and oncology·1994
Same journal

Eccrine angiomatous hamartoma.

The Journal of dermatologic surgery and oncology·1994
Same journal

Treatment of pyoderma gangrenosum with cultured keratinocyte autografts.

The Journal of dermatologic surgery and oncology·1994
See all related articles

Mohs micrographic surgery (MMS) for skin cancer is highly effective, but local recurrences, often due to procedural errors, can occur. These rare recurrences highlight the need for meticulous technique in MMS procedures.

Area of Science:

  • Dermatology
  • Surgical Oncology
  • Pathology

Background:

  • Mohs micrographic surgery (MMS) achieves high cure rates for cutaneous carcinomas, approaching 99% for 5-year survival.
  • Despite high efficacy, 100% cure rates for unifocal carcinomas are theoretically achievable but not always realized.

Purpose of the Study:

  • To investigate the reasons behind local recurrence of cutaneous malignancies following Mohs micrographic surgery.
  • To identify factors contributing to treatment failure in MMS for skin cancer.

Main Methods:

  • A retrospective analysis was conducted on all cutaneous malignancies treated with MMS over a 4-year period.
  • Recurrent lesions were meticulously examined to determine potential causes for their persistence after initial MMS treatment.

Related Experiment Videos

Main Results:

  • Out of 2,414 treated malignancies, 33 (1.4%) showed local recurrence after prior MMS.
  • Procedural or interpretation errors were identified as the cause in 77% of recurrent cases.
  • The average time to recurrence was 38.5 months, with a notable 20% of recurrences appearing more than 5 years post-MMS.

Conclusions:

  • Local recurrences after Mohs micrographic surgery are infrequent, with procedural issues being the predominant cause.
  • The established 5-year cure rates for certain skin cancers, like basal cell carcinoma, might overestimate the long-term efficacy of MMS.