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Methods for In Vivo Biomechanical Testing on Brachial Plexus in Neonatal Piglets
Published on: December 19, 2019
Continuous brachial plexus neural blockade in a child with intractable cancer pain
M G Cooper1, J P Keneally, D Kinchington
1Department of Anesthesia, Children's Hospital, Camperdown, Sydney, Australia.
Insights
Regional anesthesia with a brachial plexus catheter effectively managed severe neuropathic arm pain in a pediatric osteosarcoma patient. This technique reduced opioid dependence and improved pain control when standard methods failed.
Area of Science:
- Pediatric Oncology
- Pain Management
- Regional Anesthesia
Background:
- Osteosarcoma is a common bone cancer in children.
- Effective pain management is crucial for pediatric cancer patients.
- Neuropathic pain can be challenging to treat with opioids alone.
Observation:
- A 6-year-old boy with upper humerus osteosarcoma experienced severe neuropathic arm pain.
- High-dose morphine provided inadequate pain relief and caused side effects like somnolence and respiratory depression.
Findings:
- An interscalene brachial plexus catheter was used for regional anesthesia.
- Bupivacaine injections over 5 days significantly improved analgesia.
- The regional anesthetic technique decreased the patient's opioid requirement.
Implications:
- Regional anesthetic techniques are valuable for managing intractable neuropathic cancer pain in children.
- Brachial plexus blocks can offer an alternative or adjunct to systemic opioids.
- This case highlights the importance of multimodal pain strategies in pediatric oncology.
Abstract:
A 6-year-old boy presented with a large, rapidly growing osteosarcoma of the upper humerus and severe neuropathic arm pain. Despite large doses of morphine (100 micrograms/kg/hr), which resulted in intermittent somnolence and respiratory depression, his pain was poorly controlled. An interscalene brachial plexus catheter was inserted, and bupivacaine was injected on ten occasions over 5 days, with markedly improved analgesia and decreased opioid requirement. Cancer pain in children can be controlled by opioids in 95% of cases; however, circumstances such as intractable neuropathic pain may require specific regional anesthetic techniques.
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