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Related Experiment Videos

Ring corneal clouding in keratoconus

B A Weissman1

  • 1Jules Stein Eye Institute, Department of Ophthalmology, UCLA School of Medicine.

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|June 1, 1994
PubMed
Summary
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Corneal edema rings in keratoconic patients wearing rigid contact lenses may indicate low oxygen transmissibility (Dk/L). A Dk/L below 3 x 10(-9) may cause this clinical sign.

Area of Science:

  • Ophthalmology
  • Corneal Physiology
  • Contact Lens Technology

Background:

  • Keratoconus is a progressive eye condition affecting corneal shape.
  • Rigid gas permeable contact lenses are often used to correct vision in keratoconus.
  • Oxygen transmissibility (Dk/L) of contact lenses is crucial for corneal health.

Purpose of the Study:

  • To investigate the relationship between corneal edema rings and oxygen transmissibility in keratoconic patients.
  • To identify a threshold for oxygen transmissibility associated with this clinical finding.

Main Methods:

  • Observation of three keratoconic patients wearing McGuire design rigid contact lenses.
  • Clinical assessment for corneal edema rings.
  • Estimation of local oxygen transmissibility (Dk/L) under the contact lenses.

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Main Results:

  • Rings of corneal edema were observed in one eye of each patient.
  • The observed edema is analogous to previously reported central circular clouding (CCC).
  • Estimated Dk/L values suggest a threshold: < 3 x 10(-9) may cause edema, while >= 6 x 10(-9) may prevent it.

Conclusions:

  • Limited oxygen transmissibility of rigid contact lenses can lead to corneal edema in keratoconus.
  • Specific Dk/L values are associated with the development or prevention of this clinical sign.
  • This finding highlights the importance of appropriate lens selection for managing keratoconus.