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Published on: April 3, 2011
Thymolipoma: analysis of 27 cases
M L Rosado-de-Christenson1, R D Pugatch, C A Moran
1Department of Radiologic Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000.
Purpose:
To characterize the radiologic features of thymolipoma.
Materials And Methods:
Twenty-seven cases of thymolipoma were reviewed. Clinical, radiologic, and pathologic findings were noted.
Results:
The masses occurred in 15 male and 12 female patients (mean age, 26.7 years). All 27 tumors were in the anterior mediastinum; 22 were in the anterior inferior mediastinum. On frontal radiographs, 12 tumors simulated cardiomegaly. On lateral radiographs, 12 tumors draped over the ipsilateral hemidiaphragm, simulating diaphragmatic elevation. Computed tomographic scans (n = 11) demonstrated a mixture of fat and soft-tissue attenuation in 10 tumors corresponding to adipose and thymic elements found at microscopy. Magnetic resonance images (n = 2) demonstrated fat and soft-tissue signal intensity characteristics. Both types of studies showed a connection between tumor and thymus.
Conclusion:
Thymolipomas are anterior mediastinal masses that may conform to the shape of adjacent structures. The diagnosis is supported by imaging studies that demonstrate fat and soft tissue within the tumor.
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