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[Carcinogenic effect of 7,12-dimethylbenz(a)anthracene 5,6-oxide in mice]
Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences. Serie D: Sciences Naturelles
|July 21, 1975
Abstract:
The comparative carcinogenic activities of 7,12-dimethylbenz(a)anthracene 5,6-oxide (DMBA-5,6-oxide) and 7,12-dimethylbenz(a)anthracene (DMBA) to skin and subcutaneous tissue were studied. It was found that DMBA-5,6-oxide was less carcinogenic to both the skin and subcutaneous tissue, than DMBA. Moreover it does not show any significant initiating acitivity. The results are discussed.