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[Development of antifactor VIII circulating anticoagulant after surgery of the biliary tract]

C Huraux1, M Hidou, J F Perrier

  • 1Département d'Anesthésie-Réanimation, CHU de Brabois, Vandoeuve-lés-Nancy.

In a 25-year-old woman, admitted with a haemorrhagic syndrome following biliary surgery, an inhibitor of factor VIII was detected. As bleeding was major, she was re-operated on under perioperative administration of the anti-inhibitory coagulant complex Autoplex-T, associated with polyvalent i.v. immunoglobulins. The other therapeutic agents are also considered and their indications discussed, after a review of the circumstances of the diagnosis of this disease.

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