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Acute ammonium dichromate poisoning

K L Meert¹, J Ellis, R Aronow

¹Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit.

Annals of Emergency Medicine

|October 1, 1994

Summary

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A child died after ingesting ammonium dichromate, experiencing organ failure. Standard treatments like dialysis were ineffective, but ascorbic acid may reduce chromium toxicity.

Area of Science:

Toxicology
Pediatric Medicine
Environmental Health

Background:

Ammonium dichromate is a toxic industrial chemical.
Hexavalent chromium compounds are known for their severe toxicity.

Observation:

A pediatric case involving accidental ingestion of ammonium dichromate.
The child presented with rapid onset of multiple-organ-system failure.

Findings:

Exchange transfusion and hemodialysis failed to effectively remove chromium or improve the patient's condition.
The patient ultimately succumbed to the toxic effects.

Implications:

Ascorbic acid (vitamin C) is proposed as a potential therapeutic agent.
Immediate, high-dose ascorbic acid may reduce hexavalent chromium toxicity.

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This suggests a novel treatment approach for chromium poisoning.