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Heterotypic Three-dimensional In Vitro Modeling of Stromal-Epithelial Interactions During Ovarian Cancer Initiation and Progression

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Published on: August 28, 2012

A case of ovarian Brenner tumor with stromal estrogenic activity

Y Morimura¹, M Ohishi, K Hoshi

¹Department of Obstetrics and Gynecology, Fukushima Medical College, Japan.

Asia-Oceania Journal of Obstetrics and Gynaecology

|June 1, 1994

Abstract:

An 88-year-old menopausal Japanese female suffering from atypical genital bleeding received a left oophorectomy for a tumor of the left ovary. A vaginal smear before removal of the tumor revealed high estrogenic activity. The patient's ovarian tumor was a benign Brenner tumor and contained theca-like cells in its stroma. The pathological findings relating to these theca-like cells suggested their estrogenic activity, and a vaginal smear after removal of the tumor revealed that estrogenic activity had disappeared.

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