Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hepatitis E virus transmission to a volunteer

A Chauhan1, S Jameel, J B Dilawari

  • 1Department of Hepatology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Lancet (London, England)
|January 16, 1993
PubMed
Summary

Hepatitis E virus (HEV) causes enteric hepatitis via fecal-oral transmission. This study shows HEV can be detected in serum before symptoms, suggesting possible parenteral spread in endemic regions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electrokinetic and electro-elastic instabilities in viscoelastic microfluidic flows: suppression and augmentation in mixing efficiency.

Soft matter·2026
Same author

Contact lens delivery improves therapeutic efficacy of nintedanib in rabbit eyes with alkali burn.

Experimental eye research·2025
Same author

Treatment outcomes after pelvic exenteration with IGAM or VRAM flap reconstruction: Review of 130 consecutive cases.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2025
Same author

Elevated expression of <i>ANTXR1</i> gene in tumors is a poor prognostic biomarker for patients with bladder cancer.

Frontiers in molecular biosciences·2025
Same author

Effect of post-harvest drying period on the chemical composition of <i>Zingiber zerumbet</i> Sm. Rhizomes essential oil and its biological activities.

Physiology and molecular biology of plants : an international journal of functional plant biology·2024
Same author

Sociologists in public health: marginal observers or mainstream collaborators?

Perspectives in public health·2024

Area of Science:

  • Hepatology
  • Virology
  • Infectious Diseases

Background:

  • Hepatitis E virus (HEV) is a significant cause of acute hepatitis globally.
  • Transmission is primarily faecal-oral, leading to enteric infections.
  • HEV causes sporadic and epidemic non-A, non-B hepatitis.

Observation:

  • A single volunteer study investigated HEV transmission and disease progression.
  • Clinical and biochemical signs of infection were monitored.
  • HEV was detected in stool and serum using reverse transcription/polymerase chain amplification.

Findings:

  • HEV detection in serum preceded the appearance of clinical symptoms.
  • Immunoglobulin G (IgG) antibodies against HEV persisted for at least 2 years post-infection.

Related Experiment Videos

  • The study confirmed the correlation between clinical features and HEV detection.

    • Implications:

    • Early HEV detection in serum suggests potential for parenteral transmission routes.
    • Understanding transmission dynamics is crucial for controlling HEV in endemic areas.
    • Persistent IgG antibodies indicate long-term immune response to HEV infection.