How cancer cells evade chemotherapy: sixteenth Richard and Hinda Rosenthal Foundation Award Lecture

A whole genomic CRISPR-Cas9 screen identifies the amino acid transporter SLC43A1 (LAT3) as a major determinant of oxaliplatin sensitivity in colorectal cancer cells.

bioRxiv : the preprint server for biology·2025

Exposure to HIV-protease inhibitors selects for increased expression of P-glycoprotein (ABCB1) in Kaposi's sarcoma cells.

British journal of cancer·2011

Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications.

Clinical pharmacology and therapeutics·2009

Cyclosporin A-dependent downregulation of the Na+/Ca2+ exchanger expression.

Annals of the New York Academy of Sciences·2007

SV40 Pseudovirion gene delivery of a toxin to treat human adenocarcinomas in mice.

Cancer gene therapy·2006

Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells.

British journal of cancer·2004

Spatial Transcriptomics on a Diverse Pancreatic Cancer Cohort Reveals Race-Related Differences in Tumor Subtypes and Immune Microenvironments.

Cancer research·2026

Mechanical Stress Induces Nuclear Envelope Rupture in Melanoma Cells to Reorganize Tumor-Stromal Interactions.

Cancer research·2026

Beyond Internalization: Target Binding as the Trigger.

Cancer research·2026

Antiviral T cells doing double-duty to fight cancer.

Cancer research·2026

MEKing Room: On the Quest for New Sources of Therapeutic Index in RAS/MAPK-Driven Cancers.

Cancer research·2026

ACKR3 Establishes a Squamous-Restricted Immune Checkpoint Axis in Lung Squamous Cell Carcinoma.

Cancer research·2026

Interaction between severe postoperative complications and adjuvant chemotherapy on overall survival after upfront resection of pancreatic ductal adenocarcinoma.

Frontiers in medicine·2026

mRNA-dendritic cell antigen vaccine potentiates CD38 CAR-T Cell therapy for relapsed/refractory acute myeloid leukemia.

Theranostics·2026

Liver-resident cellular determinants of oncolytic virotherapy in hepatocellular carcinoma: viral susceptibility and spatial immune remodeling.

Frontiers in cell and developmental biology·2026

Chemokines as regulators of CAR-T cell trafficking, function, and context-dependent tumor cell death.

Frontiers in immunology·2026

Distinct prognostic impact of circumferential resection margin and adverse histologic features after intersphincteric resection for ultra-low rectal cancer following chemoradiotherapy: a retrospective cohort study.

Annals of surgical treatment and research·2026

Efficacy of the Peritoneovenous Shunt as Palliative Care for Patients with Advanced Cancer with Refractory Ascites: A Randomized Controlled Trial (JIVROSG-0803 Study).

Interventional radiology (Higashimatsuyama-shi (Japan)·2026

Related Experiment Videos

How cancer cells evade chemotherapy: sixteenth Richard and Hinda Rosenthal Foundation Award Lecture

Related Concept Videos

A whole genomic CRISPR-Cas9 screen identifies the amino acid transporter SLC43A1 (LAT3) as a major determinant of oxaliplatin sensitivity in colorectal cancer cells.

Exposure to HIV-protease inhibitors selects for increased expression of P-glycoprotein (ABCB1) in Kaposi's sarcoma cells.

Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications.

Cyclosporin A-dependent downregulation of the Na+/Ca2+ exchanger expression.

SV40 Pseudovirion gene delivery of a toxin to treat human adenocarcinomas in mice.

Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells.

Spatial Transcriptomics on a Diverse Pancreatic Cancer Cohort Reveals Race-Related Differences in Tumor Subtypes and Immune Microenvironments.

Mechanical Stress Induces Nuclear Envelope Rupture in Melanoma Cells to Reorganize Tumor-Stromal Interactions.

Beyond Internalization: Target Binding as the Trigger.

Antiviral T cells doing double-duty to fight cancer.

MEKing Room: On the Quest for New Sources of Therapeutic Index in RAS/MAPK-Driven Cancers.

ACKR3 Establishes a Squamous-Restricted Immune Checkpoint Axis in Lung Squamous Cell Carcinoma.

Interaction between severe postoperative complications and adjuvant chemotherapy on overall survival after upfront resection of pancreatic ductal adenocarcinoma.

mRNA-dendritic cell antigen vaccine potentiates CD38 CAR-T Cell therapy for relapsed/refractory acute myeloid leukemia.

Liver-resident cellular determinants of oncolytic virotherapy in hepatocellular carcinoma: viral susceptibility and spatial immune remodeling.

Chemokines as regulators of CAR-T cell trafficking, function, and context-dependent tumor cell death.

Distinct prognostic impact of circumferential resection margin and adverse histologic features after intersphincteric resection for ultra-low rectal cancer following chemoradiotherapy: a retrospective cohort study.

Efficacy of the Peritoneovenous Shunt as Palliative Care for Patients with Advanced Cancer with Refractory Ascites: A Randomized Controlled Trial (JIVROSG-0803 Study).

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How cancer cells evade chemotherapy: sixteenth Richard and Hinda Rosenthal Foundation Award Lecture

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