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The mouse lysyl oxidase gene (Lox) resides on chromosome 18
Y S Chang1, D M Svinarich, T P Yang
1Center for Molecular Biology, Wayne State University, Detroit, MI.
Cytogenetics and Cell Genetics
|January 1, 1993
Abstract:
Lysyl oxidase initiates crosslink formation of the connective tissue matrix. This enzyme can also revert the ras phenotype in mouse NIH 3T3-transformed cells. Even though lysyl oxidase may participate in many different biological processes, its chromosomal assignment in the mouse genome remains to be addressed. Southern analysis of a panel of Chinese hamster x mouse somatic cell hybrids was utilized to assign the lysyl oxidase gene (Lox) to mouse Chromosome 18.