In situ changes in purine nucleotide and N-acetyl concentrations upon inducing global ischemia in cat brain

Spectral changes upon death (global ischemia) were recorded in situ in cat cerebral cortex. A rapid signal loss of 10 +/- 4% in the N-acetyl resonance was observed (five cases), after which it remained constant for 1 h. For the first time signal changes are reported for low-field resonances, which are assigned to adenosine/inosine and hypoxanthine.