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Calbindin D-28K in the dopaminergic mesocortical projection of a monkey (Aotus trivirgatus)
P Gaspar1, C W Heizmann, J H Kaas
1Department of Psychology, Vanderbilt University, Nashville, TN.
Brain Research
|February 12, 1993
Abstract:
Injections of fluorescent dyes were made in the prefrontal and motor cortex of owl monkeys and retrogradely labeled neurons in the mesencephalon were analyzed for tyrosine hydroxylase and calbindin-D28K immunostaining. Numbers of mesocortical dopaminergic neurons in the dorsal substantia nigra compacta and in the ventral tegmental area also contain calbindin-D28K. This cortically projecting calbindin-D28K containing subpopulation of the dopaminergic mesencephalic cells may be characterized by different electrophysiological properties and a lesser vulnerability to cell death.