Tyrosine hydroxylase immunoreactivity in cerebellar Purkinje cells of the rat

M Takada1, T Sugimoto, T Hattori

  • 1Department of Anatomy and Cell Biology, University of Toronto, Ont., Canada.

Neuroscience Letters
|February 5, 1993
PubMed

Employing tyrosine hydroxylase (TH) immunohistochemistry, we have revealed that TH immunoreactivity occurs in cerebellar Purkinje cells in the rat. These TH-immunoreactive Purkinje cells were distributed predominantly in the crus I & II ansiform lobules and the paraflocculus, and to a lesser extent in the I & X vermal lobules. Since Purkinje cells in such cerebellar regions displayed no immunoreactivity to dopamine-beta-hydroxylase, the TH-immunoreactive Purkinje cells identified in the present study might contain dopamine or L-DOPA.

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