Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Relapsing polychondritis presenting as cutaneous polyarteritis nodosa

G Rauh1, I Kamilli, U Gresser

  • 1Medizinische Poliklinik, Universität München.

The Clinical Investigator
|April 1, 1993
PubMed
Summary

Relapsing polychondritis can manifest with skin conditions like cutaneous polyarteritis nodosa, which may precede cartilage inflammation. This suggests vasculitis might be an integral part of relapsing polychondritis, not a separate entity.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigation of toxicity and mutagenicity of cold atmospheric argon plasma.

Environmental and molecular mutagenesis·2017
Same author

Photodynamic therapy using intense pulsed light for treating actinic keratoses and photoaged skin of the dorsal hands: a randomized placebo-controlled study.

The British journal of dermatology·2016
Same author

Biomodulatory metronomic therapy in stage IV melanoma is well-tolerated and may induce prolonged progression-free survival, a phase I trial.

Journal of the European Academy of Dermatology and Venereology : JEADV·2015
Same author

Comparing cold-air analgesia, systemically administered analgesia and scalp nerve blocks for pain management during photodynamic therapy for actinic keratosis of the scalp presenting as field cancerization: a randomized controlled trial.

The British journal of dermatology·2014
Same author

Comparison of Erbium:YAG and Carbon Dioxide Laser for the Treatment of Facial Rhytides.

Archives of dermatology·2014
Same author

Photodynamic inactivation of staphylococci with 5-aminolaevulinic Acid or photofrin.

Lasers in medical science·2014

Area of Science:

  • Rheumatology
  • Dermatology
  • Pathology

Background:

  • Relapsing polychondritis (RP) is a rare systemic autoimmune disease targeting cartilaginous structures.
  • Dermal involvement occurs in ~25% of RP patients, but skin biopsy findings are infrequently reported.
  • Common skin lesions include leukocytoclastic vasculitis, livedo reticularis, erythema nodosum, and keratodermia blenorrhagicum.

Observation:

  • This report details a patient with relapsing polychondritis where cutaneous polyarteritis nodosa (PAN) was diagnosed six months prior to cartilage inflammation.
  • Cutaneous PAN is a rare vasculitis primarily affecting the skin, muscles, and joints, typically without visceral involvement and with a benign course.

Findings:

  • The case highlights a potential overlap between relapsing polychondritis and vasculitis.

Related Experiment Videos

  • Vasculitis is a concomitant feature in approximately 30% of relapsing polychondritis patients.

    • Implications:

    • The findings challenge the distinct classification of relapsing polychondritis and cutaneous polyarteritis nodosa.
    • Further research is warranted to elucidate the relationship between systemic inflammation and vasculitic manifestations in RP.
    • Recognizing cutaneous PAN as a potential early sign of RP may improve diagnostic timelines and patient management.