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Serum FSH, LH, and testosterone concentrations in presumably fertile men: effect of age
K H Tennekoon1, E H Karunanayake
1Department of Physiology, Faculty of Medicine, University of Colombo, Sri Lanka.
Abstract
Objective:
Delineation of change in male hormone and gonadotropin levels from age 21 to 85.
Subjects:
Healthy married volunteers with one or more children.
Methods:
A 5-mL venous blood sample, serum separated within one hour; testosterone measured by direct RIA, FSH and LH by immunoradiometric assay and magnetic separation.
Results:
FSH significantly higher from 6th decade, LH from 7th decade; testosterone lower from 6th decade.
Conclusions:
Apparently, a rise in FSH and reduction in testosterone precede a rise in LH concentration.