[Changes of endogenous opioid peptides content in RPGL during acupuncture analgesia]

By push-pull perfusion technique and RIA of neuro-peptides, it was found that after 20 minutes' electroacupunture (EA), the release of LEK from the RPGL in the EA group was significantly higher than that in the control group (P < 0.05). The release of beta-EP from the RPGL in the EA group with higher efficacy was significantly higher than that in the control group (P < 0.05), but no significant changes were found in the EA group with lower efficacy. There was a positive correlation between the changes of release of LEK or beta-EP and the increase of pain threshold. The release of DynA1-13 tends to show a barely significant extent (P > 0.05). The results indicate that acupuncture analgesia is able to increase the release of LEK and beta-EP in the RPGL.