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Immune recognition of polar pili from Pseudomonas aeruginosa O
W Smart1, P A Sastry, W Paranchych
1Department of Immunology, University of Alberta, Edmonton, Canada.
Infection and Immunity
|August 1, 1993
Abstract:
The B- and T-cell antigenic sites on type O pili from Pseudomonas aeruginosa were determined by using an antipilus antibody competition assay and PAO-immune T-cell blasts in proliferation studies. The citraconylated tryptic digest III region (residues 54 to 120) was determined to be an immunodominant site for both T and B cells on the pilin molecule.