Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bilateral undescended testes

H M Snyder1

  • 1Division of Urology, Children's Hospital of Philadelphia, PA 19104-4399.

European Journal of Pediatrics
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

The incidence of undescended testes in boys has increased. Bilateral undescended testes are associated with more central nervous system and genitourinary anomalies, suggesting a severe endocrinopathy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editorial: The Future is Now: Advancing Blood-Based Markers.

The journal of prevention of Alzheimer's disease·2022
Same author

Editorial: A Turning Point in Alzheimer's Research: Harmonized Research Strategies and Novel Investments in Public Health Infrastructure Are Reenergizing the Field, and Rekindling Hope for Those Affected by Alzheimer's and Related Dementias.

The journal of prevention of Alzheimer's disease·2019
Same author

Alzheimer's Association: Initiatives and Public Health Perspective.

The journal of prevention of Alzheimer's disease·2017
Same author

Indications for cholangiography.

The Journal of the American Osteopathic Association·2010
Same author

The present status of myelography as it pertains to the radiologist.

The Journal of the American Osteopathic Association·2010
Same author

Roentgen management of para-articular calcifications of the shoulder joint.

The Journal of the American Osteopathic Association·2010
Same journal

Ultrasound-guided midline catheters in the neonatal intensive care unit: a single-center pilot study.

European journal of pediatrics·2026
Same journal

Gastrointestinal pathogens in paediatric patients with diarrhoea during the COVID-19 pandemic in Spain: a multicentre molecular-based prospective study.

European journal of pediatrics·2026
Same journal

Low serum immunoglobulin levels in pediatric atopic dermatitis: association with disease severity and exploratory scores.

European journal of pediatrics·2026
Same journal

Safely developing respiratory care during emergency neonatal transport through systematic collection and analysis of detailed ventilator data.

European journal of pediatrics·2026
Same journal

Validity and reliability of the Turkish version of the Physical Activity Parenting Questionnaire for Children.

European journal of pediatrics·2026
Same journal

Correction to: A novel oxygenation distension index (ODI): a driving pressure-based metric compared with the oxygenation index in pediatric PARDS.

European journal of pediatrics·2026
See all related articles

Area of Science:

  • Pediatric Endocrinology
  • Urology

Background:

  • Undescended testes (cryptorchidism) management is a growing concern.
  • Incidence has risen from 0.8% to 1.6% in one-year-old boys.
  • Many cases involve hypothalamic-pituitary-gonadal axis disturbances, potentially indicating hypogonadotropic hypogonadism.

Purpose of the Study:

  • To analyze the association between bilateral undescended testes and other anomalies.
  • To investigate if bilateral cryptorchidism represents a more severe form of endocrinopathy.

Main Methods:

  • Retrospective review of patient data from The Children's Hospital of Philadelphia.
  • Comparison of central nervous system (CNS) and genitourinary (G-U) anomalies in boys with unilateral versus bilateral undescended testes.

Related Experiment Videos

Main Results:

  • Boys with bilateral undescended testes showed a significantly higher incidence of CNS abnormalities (P = 0.0000).
  • A significantly greater number of associated G-U anomalies were reported in boys with bilateral undescended testes (P = 0.0004).

Conclusions:

  • Bilateral undescended testes may represent the most severe spectrum of hypothalamic-pituitary-gonadal axis dysfunction.
  • These findings support the link between bilateral cryptorchidism and increased CNS and G-U anomalies.