Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Persistent movement disorders induced by buspirone

P A LeWitt¹, A Walters, W Hening

¹Clinical Neuroscience Program, Sinai Hospital, Detroit, Michigan.

Movement Disorders : Official Journal of the Movement Disorder Society

|July 1, 1993

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Chitin-calcium alginate composite fibers for wound care dressings spun from ionic liquid solution.

Journal of materials chemistry. B·2020

Same author

Adductor canal versus femoral triangle anatomical locations for continuous catheter analgesia after total knee arthroplasty: a multicentre randomised controlled study.

British journal of anaesthesia·2019

Same author

Topic: Recent Innovations in Hernia Surgery.

Hernia : the journal of hernias and abdominal wall surgery·2015

Same author

Density of river otters (Lontra canadensis) in relation to energy development in the Green River Basin, Wyoming.

The Science of the total environment·2015

Same author

Additional evidence that PGAP1 loss of function causes autosomal recessive global developmental delay and encephalopathy.

Clinical genetics·2015

Same author

Pericardiocentesis: a clinical anatomy review.

Clinical anatomy (New York, N.Y.)·2012

Buspirone, a nonsedative anxiolytic, can cause movement disorders like dystonia and dyskinesia. Prolonged use may lead to persistent or worsened involuntary movements in some patients.

Area of Science:

Neuroscience
Pharmacology

Background:

Buspirone is a widely used, nonsedative anxiolytic medication.
While generally safe, rare instances of movement disorders have been linked to its use.

Observation:

Two cases of persistent movement disorders following prolonged buspirone treatment are presented.
One patient developed cervical-cranial dystonia and tremors.
Another experienced worsening of pre-existing spasmodic torticollis and tardive dyskinesia, plus new involuntary phonations.

Findings:

Buspirone treatment, even at moderate doses (30-40 mg/day), can induce or exacerbate movement disorders.
These movement disorders, including dystonia and dyskinesia, may persist after drug discontinuation.

Implications:

Related Experiment Videos

Clinicians should be vigilant for movement disorder symptoms in patients taking buspirone.
Buspirone's potential to cause or worsen conditions like dystonia and dyskinesia requires careful patient monitoring.
Further research into the mechanisms underlying buspirone-induced movement disorders is warranted.