Nursing considerations in paclitaxel (Taxol) administration

The administration of paclitaxel (TAXOL) presents some challenges unique among chemotherapeutic agents. Information published and presented to date has focused primarily on the most threatening and clinically significant aspects of paclitaxel administration and resultant side effects. However, there are a number of other issues that, while not as acutely dangerous, can be very significant to the success of paclitaxel therapy and to those medical, pharmacy, and nursing personnel involved in drug administration and patient management. This review will focus on the collaborative role of the nurse in the recognition and prevention of side effects related to paclitaxel therapy. A nursing plan of care describes the pertinent paclitaxel toxicities and suggests interventions related to patient care issues.