Effect of sodium cromoglycate on asthmatic reactions to environmental temperature changes

Immediate asthmatic reactions, with falls in FEV1 of 16-42.5% were elicited by exposure in a cold room at 3 degrees C in five out of eight subjects with histories of asthma provoked by falls in environmental temperature. In four of the subjects pretreatment by inhalation of sodium cromoglycate gave complete inhibition of the asthmatic reaction in two, partial inhibition in one and had no effect in one case.