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[Therapy of allergic rhinitis]

G Rasp1

  • 1Klinik und Poliklinik für Hals-, Nasen- und Ohrenkranke, Ludwig-Maximilians-Universität München.

Laryngo- Rhino- Otologie
|August 1, 1993
PubMed
Summary

Nasal allergy, or allergic rhinitis, involves immune system changes triggering inflammation. Effective treatment requires personalized approaches, including allergen avoidance, immunotherapy, and targeted drug therapies for symptom relief.

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Area of Science:

  • Immunology
  • Allergology

Context:

  • Nasal allergy (allergic rhinitis) stems from altered individual immunoreactivity.
  • It involves B-lymphocytes producing IgE antibodies, mast cell activation, and mediator release causing inflammation.

Purpose:

  • To outline the principles of allergic rhinitis therapy.
  • To emphasize individualized treatment strategies based on patient needs.

Summary:

  • Four main therapeutic principles exist: allergen avoidance (ideal but not always feasible), immunotherapy (inducing tolerance), symptomatic drug therapy (vasoconstrictors, anticholinergics), and prophylactic agents (cromoglycate, antihistamines, steroids).
  • Drug therapies include systemic and local vasoconstrictors for congestion, anticholinergics for secretions, cromoglycate as a local prophylactic, non-sedating antihistamines, and steroids (preferably local due to side effects).

Impact:

  • Highlights the importance of personalized medicine in managing allergic rhinitis.
  • Provides a comprehensive overview of current therapeutic options for allergic rhinitis, guiding clinical practice.

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