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Method for detection of picornavirus capsid binders with soluble intercellular adhesion molecule 1
K Last-Barney1, S D Marlin, K Pal
1Department of Immunology, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut 06877.
Antimicrobial Agents and Chemotherapy
|August 1, 1993
Abstract:
A method utilizing immobilized major group rhinoviruses and biotinylated soluble intercellular adhesion molecule 1 has been developed for the detection of capsid binders. Binding measurements indicate a loss in relative affinity of biotinylated soluble intercellular adhesion molecule 1 for rhinoviruses by capsid binders. This method and a new class of capsid binders are discussed.