[Bioavailability of different brands of phenoxymethylpenicillin (author's transl)]

The bioavailability of 11 brands of phenoxymethylpenicillin was investigated in a cross-over-study in healthy volunteers. There were found some differences in the velocity of absorption, in the peaks and in the blood levels after 4 hours. The absorption rate was evaluated by comparison of area under the curve and urine-recovery after oral administration of different brands. It is suggested to control each brand of oral antibiotic preparations on bioavailability.