Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nerve conduction and temperature: necessary warming time

H Franssen1, G H Wieneke

  • 1Rudolf Magnus Research School in the Neurosciences, Department of Clinical Neurophysiology, Utrecht, The Netherlands.

Muscle & Nerve
|March 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A comparative study of brachial plexus sonography and magnetic resonance imaging in chronic inflammatory demyelinating neuropathy and multifocal motor neuropathy.

European journal of neurology·2017
Same author

Bleomycin resistance: a new dominant selectable marker for plant cell transformation.

Plant molecular biology·2013
Same author

Multifocal motor neuropathy: association of anti-GM1 IgM antibodies with clinical features.

Neurology·2010
Same author

Correlates of outcome and response to IVIg in 88 patients with multifocal motor neuropathy.

Neurology·2010
Same author

Prognosis of polyneuropathy due to IgM monoclonal gammopathy: a prospective cohort study.

Neurology·2010
Same author

Rituximab for polyneuropathy with IgM monoclonal gammopathy.

Journal of neurology, neurosurgery, and psychiatry·2009

Warming extremities before nerve conduction studies is crucial. Insufficient warming time leads to inaccurate nerve conduction velocity and compound action potential measurements, necessitating specific warming protocols for reliable results.

Area of Science:

  • Neuroscience
  • Clinical Electrophysiology

Background:

  • Accurate nerve conduction studies (NCS) are vital for diagnosing neurological disorders.
  • Extremity temperature significantly influences NCS parameters.
  • Standardized protocols for temperature equilibration are needed.

Purpose of the Study:

  • To determine the optimal warming time for extremities before NCS.
  • To quantify the impact of temperature changes on nerve conduction variables.
  • To establish correlations between initial skin temperature and required warming duration.

Main Methods:

  • Nerve conduction variables were measured in 8 healthy subjects during controlled leg cooling (18°C) and warming (36°C).
  • Measurements included nerve conduction velocity (NCV), distal motor latency (DML), and compound action potential (CMAP/CNAP) characteristics.

Related Experiment Videos

  • An exponential model described the time-course of variable changes during temperature shifts.

    • Main Results:

    • Cooling decreased NCV and increased DML, CMAP/CNAP duration, and area.
    • Warming reversed these effects, with changes diminishing over time.
    • Correlation analysis linked initial skin temperature to the warming time needed for stable NCS parameters.
    • Correction factors alone were insufficient for accurate NCV and other NCS variables.

    Conclusions:

    • Specific warming durations are required to achieve reliable NCS measurements at 36°C.
    • Temperature-dependent changes in NCS variables follow an exponential time course.
    • Relying solely on correction factors is inadequate for ensuring measurement accuracy across all NCS parameters.