Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

An iodine load from water-purification tablets alters thyroid function in humans

W J Georgitis1, M T McDermott, G S Kidd

  • 1Department of Medicine, Fitzsimons Army Medical Center, Aurora, CO 80045-5001.

Military Medicine
|December 1, 1993
PubMed
Summary

Water purification tablets containing tetraglycine hydroperiodide can temporarily affect thyroid function. Short-term use in a field setting led to mild thyroid impairment in healthy adults.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Probing morphological and compositional variations of anodized carbon electrodes with tapping-mode scanning force microscopy.

Analytical chemistry·2011
Same author

Characterization of surfactant coatings in capillary electrophoresis by atomic force microscopy.

Analytical chemistry·2001
Same author

Subclinical hypothyroidism is mild thyroid failure and should be treated.

The Journal of clinical endocrinology and metabolism·2001
Same author

Management practices among primary care physicians and thyroid specialists in the care of hypothyroid patients.

Thyroid : official journal of the American Thyroid Association·2001
Same author

The effects of region-specific resistance and aerobic exercises on bone mineral density in premenopausal women.

Military medicine·2001
Same author

Reverse transcription polymerase chain reaction analysis of pituitary hormone, Pit-1 and steroidogenic factor-1 messenger RNA expression in pituitary tumors.

Pituitary·2000

Area of Science:

  • Endocrinology
  • Environmental Health
  • Public Health

Background:

  • Tetraglycine hydroperiodide tablets are utilized for purifying drinking water in field conditions.
  • Stable iodide administration can impact thyroid function in healthy adults.

Purpose of the Study:

  • To evaluate the effects of water purification tablets on thyroid function in normal adults during a military field exercise.

Main Methods:

  • 14 healthy volunteers were studied over 2 weeks in a field environment.
  • Half received 4 tablets (32 mg free iodine) daily for 7 days; the other half served as controls.
  • Thyroid function parameters including thyroxine, triiodothyronine, and TSH were measured.

Main Results:

  • The treatment group showed a 14% reduction in thyroxine and 15% in triiodothyronine.

Related Experiment Videos

  • Basal TSH increased by 122% and TSH response to TRH by 49% in the treatment group.
  • Two subjects in the treatment group exhibited TSH levels above the normal range.

    • Conclusions:

    • One week of exposure to iodine from these water purification tablets causes mild thyroid function impairment in humans.
    • The effects were transient and observed in a controlled field setting.
    • Further research may be needed to understand long-term implications.