The value of pregnancy-associated alpha2-glycoprotein in patients with colorectal cancer

Serum pregnancy-associated alpha2-glycoprotein (alpha2PAG) levels have been measured in 67 patients with colorectal cancer. Postoperative changes in alpha2PAG concentrations were observed in patients undergoing apparently curative surgery and compared with results in patients with residual local or metastatic tumour. Significant increase in alpha2PAG levels were found only in those patients with residual or disseminated tumour. In this study alpha2PAG levels closely paralleled the clinical course of the disease in many patients.